Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED31538.1Cyclase family protein; [R] COG1878 Predicted metal-dependent hydrolase. (275 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
  
 
 0.880
EED33371.1
Monooxygenase, FAD-binding; [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
 
  
  0.835
EED33373.1
Glyoxalase/bleomycin resistance protein/dioxygenase; [E] COG0346 Lactoylglutathione lyase and related lyases.
 
     0.771
EED33374.1
Conserved hypothetical protein; [E] COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases.
 
     0.770
EED33454.1
Putative Phosphate acetyl/butyryl transferase subfamily; [C] COG0281 Malic enzyme.
     
  0.739
NOR53_376
Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.739
oadA
Oxaloacetate decarboxylase alpha subunit; [I] COG0511 Biotin carboxyl carrier protein.
     
  0.700
EED31537.1
Amidohydrolase family protein; [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold.
       0.682
EED32354.1
[S] COG3246 Uncharacterized conserved protein.
  
    0.673
EED33375.1
Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.549
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (14%) [HD]