Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOR53_264Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (298 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
     0.732
EED32260.1
Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.654
pssA
CDP-diacylglycerol--serine O-phosphatidyltransferase; [I] COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.642
EED32774.1
[K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.516
EED32842.1
Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.446
EED32895.1
Hypothetical protein; [K] COG0583 Transcriptional regulator; CBS; Belongs to the LysR transcriptional regulatory family.
  
     0.443
NOR53_728
Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.428
EED32861.1
Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.421
EED32104.1
[K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.413
NOR53_155
[K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.411
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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