tlyC protein (gamma proteobacterium NOR53) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

tlyC

Magnesium and cobalt efflux protein CorC; [R] COG0517 FOG: CBS domain. (282 aa)

Predicted Functional Partners:

ybeY

0.981

EED31349.1

0.952

lnt

0.919

miaB

0.720

guaA

0.682

leuS

0.626

holA

0.615

lptE

0.577

mgtE

0.575

EED31347.1

0.534

Your Current Organism:

gamma proteobacterium NOR53

NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EED31347.1	EED31349.1	NOR53_2464	NOR53_2710	[S] COG4517 Uncharacterized protein conserved in bacteria.	PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.	0.534
EED31347.1	lnt	NOR53_2464	NOR53_2615	[S] COG4517 Uncharacterized protein conserved in bacteria.	Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.	0.522
EED31347.1	miaB	NOR53_2464	NOR53_2542	[S] COG4517 Uncharacterized protein conserved in bacteria.	tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.	0.589
EED31347.1	tlyC	NOR53_2464	NOR53_2640	[S] COG4517 Uncharacterized protein conserved in bacteria.	Magnesium and cobalt efflux protein CorC; [R] COG0517 FOG: CBS domain.	0.534
EED31347.1	ybeY	NOR53_2464	NOR53_2647	[S] COG4517 Uncharacterized protein conserved in bacteria.	Putative metalloprotease H16_A0526; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.534
EED31349.1	EED31347.1	NOR53_2710	NOR53_2464	PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.	[S] COG4517 Uncharacterized protein conserved in bacteria.	0.534
EED31349.1	holA	NOR53_2710	NOR53_2484	PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.	[L] COG1466 DNA polymerase III, delta subunit.	0.629
EED31349.1	leuS	NOR53_2710	NOR53_2421	PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.	[J] COG0060 Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.626
EED31349.1	lnt	NOR53_2710	NOR53_2615	PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.	Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.	0.886
EED31349.1	lptE	NOR53_2710	NOR53_2861	PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.	Lipoprotein, putative; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.	0.571
EED31349.1	miaB	NOR53_2710	NOR53_2542	PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.	tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.	0.724
EED31349.1	tlyC	NOR53_2710	NOR53_2640	PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.	Magnesium and cobalt efflux protein CorC; [R] COG0517 FOG: CBS domain.	0.952
EED31349.1	ybeY	NOR53_2710	NOR53_2647	PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.	Putative metalloprotease H16_A0526; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.985
guaA	leuS	NOR53_772	NOR53_2421	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	[J] COG0060 Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.502
guaA	mgtE	NOR53_772	NOR53_797	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	Magnesium transporter; Acts as a magnesium transporter.	0.812
guaA	tlyC	NOR53_772	NOR53_2640	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	Magnesium and cobalt efflux protein CorC; [R] COG0517 FOG: CBS domain.	0.682
holA	EED31349.1	NOR53_2484	NOR53_2710	[L] COG1466 DNA polymerase III, delta subunit.	PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.	0.629
holA	leuS	NOR53_2484	NOR53_2421	[L] COG1466 DNA polymerase III, delta subunit.	[J] COG0060 Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.808
holA	lnt	NOR53_2484	NOR53_2615	[L] COG1466 DNA polymerase III, delta subunit.	Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.	0.623
holA	lptE	NOR53_2484	NOR53_2861	[L] COG1466 DNA polymerase III, delta subunit.	Lipoprotein, putative; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.	0.869