| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31694.1 | EED32226.1 | NOR53_3272 | NOR53_2965 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | [E] COG0070 Glutamate synthase domain 3. | 0.885 |
| EED31694.1 | argD | NOR53_3272 | NOR53_2708 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.774 |
| EED31694.1 | argG | NOR53_3272 | NOR53_2608 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | [E] COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.420 |
| EED31694.1 | carA | NOR53_3272 | NOR53_2431 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Carbamoyl-phosphate synthase, small subunit; [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II; Belongs to the CarA family. | 0.998 |
| EED31694.1 | carB | NOR53_3272 | NOR53_2705 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Carbamoyl-phosphate synthase, large subunit; [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; Belongs to the CarB family. | 0.999 |
| EED31694.1 | purF | NOR53_3272 | NOR53_1335 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.830 |
| EED31694.1 | purL | NOR53_3272 | NOR53_919 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.921 |
| EED31694.1 | pyrB | NOR53_3272 | NOR53_392 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | [F] COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.999 |
| EED31694.1 | pyrE | NOR53_3272 | NOR53_3120 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.999 |
| EED31694.1 | pyrF | NOR53_3272 | NOR53_1429 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.999 |
| EED32226.1 | EED31694.1 | NOR53_2965 | NOR53_3272 | [E] COG0070 Glutamate synthase domain 3. | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | 0.885 |
| EED32226.1 | argD | NOR53_2965 | NOR53_2708 | [E] COG0070 Glutamate synthase domain 3. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.719 |
| EED32226.1 | argG | NOR53_2965 | NOR53_2608 | [E] COG0070 Glutamate synthase domain 3. | [E] COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.927 |
| EED32226.1 | carA | NOR53_2965 | NOR53_2431 | [E] COG0070 Glutamate synthase domain 3. | Carbamoyl-phosphate synthase, small subunit; [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II; Belongs to the CarA family. | 0.821 |
| EED32226.1 | carB | NOR53_2965 | NOR53_2705 | [E] COG0070 Glutamate synthase domain 3. | Carbamoyl-phosphate synthase, large subunit; [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; Belongs to the CarB family. | 0.931 |
| EED32226.1 | purF | NOR53_2965 | NOR53_1335 | [E] COG0070 Glutamate synthase domain 3. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.828 |
| EED32226.1 | purL | NOR53_2965 | NOR53_919 | [E] COG0070 Glutamate synthase domain 3. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.902 |
| argD | EED31694.1 | NOR53_2708 | NOR53_3272 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | 0.774 |
| argD | EED32226.1 | NOR53_2708 | NOR53_2965 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | [E] COG0070 Glutamate synthase domain 3. | 0.719 |
| argD | argG | NOR53_2708 | NOR53_2608 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | [E] COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.999 |