Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aspC[E] COG1448 Aspartate/tyrosine/aromatic aminotransferase. (395 aa)    
Predicted Functional Partners:
EED33765.1
P-protein; [E] COG1605 Chorismate mutase.
    
 0.957
hppD
[ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.
  
 
 0.932
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
 0.894
NOR53_188
[E] COG3186 Phenylalanine-4-hydroxylase.
  
 
 0.869
EED32486.1
Asparate kinase, monofunctional class; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family.
  
 
 0.850
gltA
[C] COG0372 Citrate synthase; Belongs to the citrate synthase family.
   
 0.839
gdhA
[E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.831
argA_1
Amino-acid N-acetyltransferase; [E] COG1246 N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family. ArgA subfamily.
  
  
 0.821
NOR53_376
Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.815
NOR53_564
[R] COG0656 Aldo/keto reductases, related to diketogulonate reductase.
   
 0.806
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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