Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
vanYVanY protein; [M] COG1876 D-alanyl-D-alanine carboxypeptidase. (250 aa)    
Predicted Functional Partners:
dacA
D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; [M] COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.605
EED31392.1
Putative Rieske [2Fe-2S] domain; [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.
       0.576
ftsI
Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.568
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
     
 0.568
EED32218.1
[M] COG0768 Cell division protein FtsI/penicillin-binding protein 2.
     
  0.543
EED32681.1
Conserved hypothetical protein; [R] COG3897 Predicted methyltransferase.
  
     0.538
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
     
 0.520
EED33036.1
leucyl/phenylalanyl-tRNA--protein transferase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.519
EED32313.1
Carbohydrate-binding family V/XII.
    
  0.518
EED32040.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.514
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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