STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EED31311.1Phage integrase family protein; [L] COG4973 Site-specific recombinase XerC; Belongs to the 'phage' integrase family. (399 aa)    
Predicted Functional Partners:
EED31312.1
Conserved hypothetical protein.
 
     0.946
EED31250.1
Conserved hypothetical protein.
 
   
 0.779
EED31249.1
Conserved hypothetical protein.
 
     0.777
EED32237.1
Phosphoribosyltransferase; [R] COG1040 Predicted amidophosphoribosyltransferases.
   
    0.543
fadJ
Fatty acid oxidation complex, alpha subunit; [I] COG1250 3-hydroxyacyl-CoA dehydrogenase.
   
 
  0.533
fadB
Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
   
 
  0.533
EED33764.1
[E] COG0287 Prephenate dehydrogenase.
  
    0.527
EED32881.1
Hypothetical protein; [S] COG2135 Uncharacterized conserved protein; Belongs to the SOS response-associated peptidase family.
   
    0.516
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.503
EED31271.1
Hypothetical protein.
  
  
 0.432
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.