| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31528.1 | NOR53_279 | NOR53_2782 | NOR53_279 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.692 |
| EED31528.1 | metH | NOR53_2782 | NOR53_1222 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.688 |
| NOR53_279 | EED31528.1 | NOR53_279 | NOR53_2782 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.692 |
| NOR53_279 | NOR53_376 | NOR53_279 | NOR53_376 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.823 |
| NOR53_279 | ileS | NOR53_279 | NOR53_185 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.651 |
| NOR53_279 | metH | NOR53_279 | NOR53_1222 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.711 |
| NOR53_279 | mviN | NOR53_279 | NOR53_277 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.799 |
| NOR53_279 | nadE | NOR53_279 | NOR53_149 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.657 |
| NOR53_279 | prs | NOR53_279 | NOR53_1305 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | ribose-Phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.666 |
| NOR53_279 | pyrB | NOR53_279 | NOR53_392 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | [F] COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.799 |
| NOR53_279 | ribF | NOR53_279 | NOR53_124 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | 0.722 |
| NOR53_279 | ubiX | NOR53_279 | NOR53_3579 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.647 |
| NOR53_376 | NOR53_279 | NOR53_376 | NOR53_279 | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.823 |
| NOR53_376 | ileS | NOR53_376 | NOR53_185 | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.520 |
| NOR53_376 | mviN | NOR53_376 | NOR53_277 | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.682 |
| NOR53_376 | nadE | NOR53_376 | NOR53_149 | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.825 |
| NOR53_376 | pyrB | NOR53_376 | NOR53_392 | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | [F] COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.727 |
| NOR53_376 | ribF | NOR53_376 | NOR53_124 | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | 0.515 |
| ileS | NOR53_279 | NOR53_185 | NOR53_279 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.651 |
| ileS | NOR53_376 | NOR53_185 | NOR53_376 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.520 |