| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31528.1 | EED32586.1 | NOR53_2782 | NOR53_2381 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. | 0.733 |
| EED31528.1 | NOR53_279 | NOR53_2782 | NOR53_279 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.680 |
| EED31528.1 | metH | NOR53_2782 | NOR53_1222 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.552 |
| EED31664.1 | NOR53_279 | NOR53_3171 | NOR53_279 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.641 |
| EED31664.1 | NOR53_376 | NOR53_3171 | NOR53_376 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.611 |
| EED31664.1 | metH | NOR53_3171 | NOR53_1222 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.773 |
| EED31664.1 | nadE | NOR53_3171 | NOR53_149 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.693 |
| EED32586.1 | EED31528.1 | NOR53_2381 | NOR53_2782 | Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.733 |
| EED32586.1 | NOR53_279 | NOR53_2381 | NOR53_279 | Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.644 |
| EED32586.1 | ribF | NOR53_2381 | NOR53_124 | Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | 0.650 |
| NOR53_279 | EED31528.1 | NOR53_279 | NOR53_2782 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.680 |
| NOR53_279 | EED31664.1 | NOR53_279 | NOR53_3171 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.641 |
| NOR53_279 | EED32586.1 | NOR53_279 | NOR53_2381 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. | 0.644 |
| NOR53_279 | NOR53_376 | NOR53_279 | NOR53_376 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.861 |
| NOR53_279 | cinA | NOR53_279 | NOR53_194 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.716 |
| NOR53_279 | metH | NOR53_279 | NOR53_1222 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.697 |
| NOR53_279 | mviN | NOR53_279 | NOR53_277 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.788 |
| NOR53_279 | nadE | NOR53_279 | NOR53_149 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.742 |
| NOR53_279 | pyrB | NOR53_279 | NOR53_392 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | [F] COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.789 |
| NOR53_279 | ribF | NOR53_279 | NOR53_124 | Nucleoside diphosphate pyrophosphatase; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | 0.748 |