Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED31526.1[O] COG0695 Glutaredoxin and related proteins; Belongs to the glutaredoxin family. Monothiol subfamily. (106 aa)    
Predicted Functional Partners:
EED32690.1
BolA family protein; [T] COG0271 Stress-induced morphogen (activity unknown); Belongs to the BolA/IbaG family.
 
 0.981
yhgI
IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.952
EED33877.1
BolA-like protein; [T] COG0271 Stress-induced morphogen (activity unknown); Belongs to the BolA/IbaG family.
 
 
 0.933
sufD
FeS assembly protein SufD; [O] COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
     
 0.856
grxC
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
 0.856
sufB
FeS assembly protein SufB; [O] COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
     
 0.830
sufC
FeS assembly ATPase SufC; [R] COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase.
     
  0.819
EED31647.1
ATPase; [S] COG0316 Uncharacterized conserved protein; Belongs to the HesB/IscA family.
 
 0.813
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 
  0.812
erpA
HesB/YadR/YfhF; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 0.809
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (12%) [HD]