Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED31597.1Ammonium transporter; [P] COG0004 Ammonia permease. (413 aa)    
Predicted Functional Partners:
EED31595.1
[E] COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
 0.999
EED31598.1
[E] COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
 0.999
glnL
Nitrogen regulation protein NR (II); [T] COG0642 Signal transduction histidine kinase.
  
 
 0.882
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
 
  
 0.858
EED31684.1
Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase.
 
 0.715
glnD
protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
   
 0.685
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.677
EED31642.1
Hdod domain family protein; [T] COG1639 Predicted signal transduction protein.
  
 
 0.646
bchL
Light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
  
  
 0.642
NOR53_215
[T] COG0642 Signal transduction histidine kinase.
  
 0.625
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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