| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31497.1 | ubiA | NOR53_2722 | NOR53_2911 | Thioesterase family protein; [R] COG0824 Predicted thioesterase. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.647 |
| EED31497.1 | ubiC | NOR53_2722 | NOR53_2934 | Thioesterase family protein; [R] COG0824 Predicted thioesterase. | Putative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.647 |
| EED31946.1 | rubB_2 | NOR53_3507 | NOR53_3399 | [S] COG3146 Uncharacterized protein conserved in bacteria. | Rubredoxin reductase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Belongs to the FAD-dependent oxidoreductase family. | 0.531 |
| EED31946.1 | ubiA | NOR53_3507 | NOR53_2911 | [S] COG3146 Uncharacterized protein conserved in bacteria. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.786 |
| EED31946.1 | ubiC | NOR53_3507 | NOR53_2934 | [S] COG3146 Uncharacterized protein conserved in bacteria. | Putative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.709 |
| EED33765.1 | NOR53_188 | NOR53_1994 | NOR53_188 | P-protein; [E] COG1605 Chorismate mutase. | [E] COG3186 Phenylalanine-4-hydroxylase. | 0.885 |
| EED33765.1 | NOR53_609 | NOR53_1994 | NOR53_609 | P-protein; [E] COG1605 Chorismate mutase. | Anthranilate synthase component II (Glutamine amido-transferase); [EF] COG0505 Carbamoylphosphate synthase small subunit. | 0.923 |
| EED33765.1 | aroC | NOR53_1994 | NOR53_865 | P-protein; [E] COG1605 Chorismate mutase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.979 |
| EED33765.1 | aspC | NOR53_1994 | NOR53_2706 | P-protein; [E] COG1605 Chorismate mutase. | [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.957 |
| EED33765.1 | trpE | NOR53_1994 | NOR53_644 | P-protein; [E] COG1605 Chorismate mutase. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.932 |
| EED33765.1 | ubiC | NOR53_1994 | NOR53_2934 | P-protein; [E] COG1605 Chorismate mutase. | Putative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.865 |
| NOR53_188 | EED33765.1 | NOR53_188 | NOR53_1994 | [E] COG3186 Phenylalanine-4-hydroxylase. | P-protein; [E] COG1605 Chorismate mutase. | 0.885 |
| NOR53_188 | aspC | NOR53_188 | NOR53_2706 | [E] COG3186 Phenylalanine-4-hydroxylase. | [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.869 |
| NOR53_188 | ubiC | NOR53_188 | NOR53_2934 | [E] COG3186 Phenylalanine-4-hydroxylase. | Putative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.647 |
| NOR53_609 | EED33765.1 | NOR53_609 | NOR53_1994 | Anthranilate synthase component II (Glutamine amido-transferase); [EF] COG0505 Carbamoylphosphate synthase small subunit. | P-protein; [E] COG1605 Chorismate mutase. | 0.923 |
| NOR53_609 | aroC | NOR53_609 | NOR53_865 | Anthranilate synthase component II (Glutamine amido-transferase); [EF] COG0505 Carbamoylphosphate synthase small subunit. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.844 |
| NOR53_609 | trpE | NOR53_609 | NOR53_644 | Anthranilate synthase component II (Glutamine amido-transferase); [EF] COG0505 Carbamoylphosphate synthase small subunit. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
| NOR53_609 | ubiC | NOR53_609 | NOR53_2934 | Anthranilate synthase component II (Glutamine amido-transferase); [EF] COG0505 Carbamoylphosphate synthase small subunit. | Putative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.652 |
| aroC | EED33765.1 | NOR53_865 | NOR53_1994 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | P-protein; [E] COG1605 Chorismate mutase. | 0.979 |
| aroC | NOR53_609 | NOR53_865 | NOR53_609 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component II (Glutamine amido-transferase); [EF] COG0505 Carbamoylphosphate synthase small subunit. | 0.844 |
