EED32327.1 protein (gamma proteobacterium NOR53)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

EED32327.1

N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold. (417 aa)

Predicted Functional Partners:

EED32326.1

0.731

EED33076.1

0.635

hppA

0.618

ahcY

0.584

NOR53_618

0.517

NOR53_399

0.508

EED32230.1

0.486

trmB

0.486

xdhB

0.485

xdhA

0.473

Your Current Organism:

gamma proteobacterium NOR53

NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EED32230.1	EED32327.1	NOR53_2948	NOR53_2964	Putative methyltransferase; [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase.	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	0.486
EED32230.1	trmB	NOR53_2948	NOR53_3680	Putative methyltransferase; [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase.	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.	0.909
EED32326.1	EED32327.1	NOR53_3121	NOR53_2964	[P] COG0659 Sulfate permease and related transporters (MFS superfamily).	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	0.731
EED32326.1	hppA	NOR53_3121	NOR53_3516	[P] COG0659 Sulfate permease and related transporters (MFS superfamily).	V-type H(+)-translocating pyrophosphatase; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.	0.543
EED32327.1	EED32230.1	NOR53_2964	NOR53_2948	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	Putative methyltransferase; [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase.	0.486
EED32327.1	EED32326.1	NOR53_2964	NOR53_3121	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	[P] COG0659 Sulfate permease and related transporters (MFS superfamily).	0.731
EED32327.1	EED33076.1	NOR53_2964	NOR53_1639	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	0.635
EED32327.1	NOR53_399	NOR53_2964	NOR53_399	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	[S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.	0.508
EED32327.1	NOR53_618	NOR53_2964	NOR53_618	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	[E] COG3741 N-formylglutamate amidohydrolase.	0.517
EED32327.1	ahcY	NOR53_2964	NOR53_3085	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.584
EED32327.1	hppA	NOR53_2964	NOR53_3516	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	V-type H(+)-translocating pyrophosphatase; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.	0.618
EED32327.1	trmB	NOR53_2964	NOR53_3680	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.	0.486
EED32327.1	xdhA	NOR53_2964	NOR53_1159	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	[C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.	0.473
EED32327.1	xdhB	NOR53_2964	NOR53_1221	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	Xanthine dehydrogenase, molybdopterin binding subunit; [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.	0.485
EED33076.1	EED32327.1	NOR53_1639	NOR53_2964	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	0.635
EED33076.1	NOR53_399	NOR53_1639	NOR53_399	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	[S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.	0.659
EED33076.1	xdhA	NOR53_1639	NOR53_1159	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	[C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.	0.647
EED33076.1	xdhB	NOR53_1639	NOR53_1221	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	Xanthine dehydrogenase, molybdopterin binding subunit; [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.	0.663
NOR53_399	EED32327.1	NOR53_399	NOR53_2964	[S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.	N-ethylammeline chlorohydrolase; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.	0.508
NOR53_399	EED33076.1	NOR53_399	NOR53_1639	[S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	0.659