Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
gshBGlutathione synthase; [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the prokaryotic GSH synthase family. (318 aa)    
Predicted Functional Partners:
gshA
Glutamate--cysteine ligase; [H] COG2918 Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
  
 
 0.921
EED31901.1
[M] COG0810 Periplasmic protein TonB, links inner and outer membranes.
      0.855
EED31903.1
Conserved hypothetical protein TIGR00250; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
 
  
 0.852
EED31902.1
Conserved hypothetical protein; [K] COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.
 
   
 0.844
gor
Glutathione reductase; Maintains high levels of reduced glutathione.
  
  
 0.830
pepA
Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.752
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
     
 0.740
gstch
[O] COG0625 Glutathione S-transferase.
  
  
 0.739
EED31511.1
[O] COG0386 Glutathione peroxidase; Belongs to the glutathione peroxidase family.
    
 0.725
EED31899.1
PAS/PAC sensor signal transduction histidine kinase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
  
  
 0.720
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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