Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iunH_2[F] COG1957 Inosine-uridine nucleoside N-ribohydrolase; Belongs to the IUNH family. (320 aa)    
Predicted Functional Partners:
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
 
 0.856
NOR53_18
Hypothetical protein; [R] COG1073 Hydrolases of the alpha/beta superfamily.
 
 
  0.800
EED32306.1
HI0933-like protein; [C] COG1252 NADH dehydrogenase, FAD-containing subunit.
       0.773
EED32307.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
       0.773
EED32308.1
Acyl CoA thioester hydrolase family protein; [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.
       0.773
EED32309.1
Conserved hypothetical protein.
       0.773
udk
Uridine kinase; [H] COG1072 Panthothenate kinase.
   
 0.649
adeC
[F] COG1001 Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
 
  
  0.619
xdhB
Xanthine dehydrogenase, molybdopterin binding subunit; [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.
    
  0.612
polA
DNA polymerase I superfamily protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.603
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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