Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED32242.1Transcriptional regulator, AlpA family; [K] COG3311 Predicted transcriptional regulator. (82 aa)    
Predicted Functional Partners:
EED31664.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
     
 0.793
EED32241.1
DNA integration/recombination/inversion protein; [L] COG0582 Integrase; Belongs to the 'phage' integrase family.
 
  
 0.788
NOR53_376
Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
  0.770
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
    
  0.756
EED33454.1
Putative Phosphate acetyl/butyryl transferase subfamily; [C] COG0281 Malic enzyme.
     
 0.754
EED32900.1
[I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).
     
  0.739
EED32676.1
Putative methylmalonyl-CoA decarboxylasealpha-subunit; [I] COG0825 Acetyl-CoA carboxylase alpha subunit.
     
  0.651
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
     
 0.572
nadC
Nicotinate-nucleotide diphosphorylase (carboxylating); [H] COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
     
  0.511
EED33192.1
Bacterial NAD-glutamate dehydrogenase superfamily protein; [E] COG2902 NAD-specific glutamate dehydrogenase.
     
  0.511
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.