Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
amiB[M] COG0860 N-acetylmuramoyl-L-alanine amidase. (430 aa)    
Predicted Functional Partners:
EED32157.1
Membrane-bound metallopeptidase; [M] COG0739 Membrane proteins related to metalloendopeptidases.
 
 
 
 0.945
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
  
 0.909
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
    
 0.902
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
     
 0.883
cinA
Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.
 
  
  0.857
NOR53_750
[M] COG2951 Membrane-bound lytic murein transglycosylase B.
    
 0.844
cpoB
Tetratricopeptide TPR_2 repeat protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
 
  
 0.824
NOR53_514
3'-5' exoribonuclease, VacB and RNase II; [M] COG3061 Cell envelope opacity-associated protein A.
 
  
 0.811
EED33201.1
Rhomboid family protein; [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).
   
   0.800
flgJ
Flagellar rod assembly protein/muramidase FlgJ; [NU] COG1705 Muramidase (flagellum-specific).
    
 0.799
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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