| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31597.1 | EED31684.1 | NOR53_2913 | NOR53_3341 | Ammonium transporter; [P] COG0004 Ammonia permease. | Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. | 0.715 |
| EED31597.1 | EED33682.1 | NOR53_2913 | NOR53_2196 | Ammonium transporter; [P] COG0004 Ammonia permease. | [T] COG0642 Signal transduction histidine kinase. | 0.624 |
| EED31597.1 | NOR53_215 | NOR53_2913 | NOR53_215 | Ammonium transporter; [P] COG0004 Ammonia permease. | [T] COG0642 Signal transduction histidine kinase. | 0.625 |
| EED31597.1 | glnD | NOR53_2913 | NOR53_1567 | Ammonium transporter; [P] COG0004 Ammonia permease. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.685 |
| EED31597.1 | glnE | NOR53_2913 | NOR53_3242 | Ammonium transporter; [P] COG0004 Ammonia permease. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.560 |
| EED31684.1 | EED31597.1 | NOR53_3341 | NOR53_2913 | Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. | Ammonium transporter; [P] COG0004 Ammonia permease. | 0.715 |
| EED31684.1 | EED33682.1 | NOR53_3341 | NOR53_2196 | Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. | [T] COG0642 Signal transduction histidine kinase. | 0.999 |
| EED31684.1 | NOR53_215 | NOR53_3341 | NOR53_215 | Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. | [T] COG0642 Signal transduction histidine kinase. | 0.999 |
| EED31684.1 | glnE | NOR53_3341 | NOR53_3242 | Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.607 |
| EED32083.1 | EED32084.1 | NOR53_3460 | NOR53_3645 | Conserved hypothetical protein TIGR00153; [P] COG1392 Phosphate transport regulator (distant homolog of PhoU). | Type II secretion system protein E; [U] COG4962 Flp pilus assembly protein, ATPase CpaF. | 0.537 |
| EED32083.1 | glnE | NOR53_3460 | NOR53_3242 | Conserved hypothetical protein TIGR00153; [P] COG1392 Phosphate transport regulator (distant homolog of PhoU). | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.522 |
| EED32084.1 | EED32083.1 | NOR53_3645 | NOR53_3460 | Type II secretion system protein E; [U] COG4962 Flp pilus assembly protein, ATPase CpaF. | Conserved hypothetical protein TIGR00153; [P] COG1392 Phosphate transport regulator (distant homolog of PhoU). | 0.537 |
| EED32084.1 | EED32087.1 | NOR53_3645 | NOR53_3681 | Type II secretion system protein E; [U] COG4962 Flp pilus assembly protein, ATPase CpaF. | [R] COG1647 Esterase/lipase. | 0.412 |
| EED32084.1 | glnE | NOR53_3645 | NOR53_3242 | Type II secretion system protein E; [U] COG4962 Flp pilus assembly protein, ATPase CpaF. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.625 |
| EED32084.1 | ilvE | NOR53_3645 | NOR53_3658 | Type II secretion system protein E; [U] COG4962 Flp pilus assembly protein, ATPase CpaF. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.499 |
| EED32087.1 | EED32084.1 | NOR53_3681 | NOR53_3645 | [R] COG1647 Esterase/lipase. | Type II secretion system protein E; [U] COG4962 Flp pilus assembly protein, ATPase CpaF. | 0.412 |
| EED32087.1 | glnE | NOR53_3681 | NOR53_3242 | [R] COG1647 Esterase/lipase. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.557 |
| EED32087.1 | ilvE | NOR53_3681 | NOR53_3658 | [R] COG1647 Esterase/lipase. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.647 |
| EED33682.1 | EED31597.1 | NOR53_2196 | NOR53_2913 | [T] COG0642 Signal transduction histidine kinase. | Ammonium transporter; [P] COG0004 Ammonia permease. | 0.624 |
| EED33682.1 | EED31684.1 | NOR53_2196 | NOR53_3341 | [T] COG0642 Signal transduction histidine kinase. | Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. | 0.999 |
