Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED32339.1[T] COG2199 FOG: GGDEF domain. (321 aa)    
Predicted Functional Partners:
EED32335.1
Hypothetical protein; [T] COG2200 FOG: EAL domain; pas:ggdef.
 
 0.920
NOR53_559
Diguanylate cyclaSe/phosphodiesterase with PAS/PAC sensor(s); [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins.
 
 0.913
EED31191.1
[T] COG2200 FOG: EAL domain.
 
 
 0.880
NOR53_789
[T] COG2199 FOG: GGDEF domain.
 
 0.873
EED34034.1
Response regulator/sensory box/ggdef domain/eal domain protein; [T] COG2200 FOG: EAL domain.
 
  0.866
EED31684.1
Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase.
 
 0.847
EED32708.1
PAS sensor diguanylate cyclase and phophodiesterase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
  0.820
EED33223.1
Diguanylate cyclase with PAS/PAC sensor; [T] COG2199 FOG: GGDEF domain.
 
 
  0.819
NOR53_335
Diguanylate cyclase; [T] COG2199 FOG: GGDEF domain.
 
 
  0.814
morA
Developmental regulator MorA; [T] COG2200 FOG: EAL domain.
  
  0.806
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (16%) [HD]