| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31592.1 | EED31594.1 | NOR53_3333 | NOR53_3323 | [S] COG3159 Uncharacterized protein conserved in bacteria. | [R] COG1011 Predicted hydrolase (HAD superfamily). | 0.850 |
| EED31592.1 | ribD | NOR53_3333 | NOR53_268 | [S] COG3159 Uncharacterized protein conserved in bacteria. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.499 |
| EED31592.1 | xerC | NOR53_3333 | NOR53_3068 | [S] COG3159 Uncharacterized protein conserved in bacteria. | Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.894 |
| EED31594.1 | EED31592.1 | NOR53_3323 | NOR53_3333 | [R] COG1011 Predicted hydrolase (HAD superfamily). | [S] COG3159 Uncharacterized protein conserved in bacteria. | 0.850 |
| EED31594.1 | EED31694.1 | NOR53_3323 | NOR53_3272 | [R] COG1011 Predicted hydrolase (HAD superfamily). | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | 0.736 |
| EED31594.1 | EED32728.1 | NOR53_3323 | NOR53_2076 | [R] COG1011 Predicted hydrolase (HAD superfamily). | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | 0.618 |
| EED31594.1 | cinA | NOR53_3323 | NOR53_194 | [R] COG1011 Predicted hydrolase (HAD superfamily). | Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.738 |
| EED31594.1 | guaA | NOR53_3323 | NOR53_772 | [R] COG1011 Predicted hydrolase (HAD superfamily). | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.719 |
| EED31594.1 | guaB | NOR53_3323 | NOR53_981 | [R] COG1011 Predicted hydrolase (HAD superfamily). | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.724 |
| EED31594.1 | nadD | NOR53_3323 | NOR53_2825 | [R] COG1011 Predicted hydrolase (HAD superfamily). | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.615 |
| EED31594.1 | ribD | NOR53_3323 | NOR53_268 | [R] COG1011 Predicted hydrolase (HAD superfamily). | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.829 |
| EED31594.1 | ribF | NOR53_3323 | NOR53_124 | [R] COG1011 Predicted hydrolase (HAD superfamily). | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | 0.634 |
| EED31594.1 | xerC | NOR53_3323 | NOR53_3068 | [R] COG1011 Predicted hydrolase (HAD superfamily). | Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.813 |
| EED31694.1 | EED31594.1 | NOR53_3272 | NOR53_3323 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | [R] COG1011 Predicted hydrolase (HAD superfamily). | 0.736 |
| EED31694.1 | EED32728.1 | NOR53_3272 | NOR53_2076 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | 0.578 |
| EED31694.1 | guaA | NOR53_3272 | NOR53_772 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.911 |
| EED31694.1 | guaB | NOR53_3272 | NOR53_981 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.882 |
| EED31694.1 | ribD | NOR53_3272 | NOR53_268 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.488 |
| EED31694.1 | ribF | NOR53_3272 | NOR53_124 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Riboflavin biosynthesis protein RibF; [H] COG0196 FAD synthase; Belongs to the ribF family. | 0.694 |
| EED32728.1 | EED31594.1 | NOR53_2076 | NOR53_3323 | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | [R] COG1011 Predicted hydrolase (HAD superfamily). | 0.618 |