Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED31684.1Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. (675 aa)    
Predicted Functional Partners:
EED34033.1
CheB methylesterase/CheR methyltransferase; [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
 0.999
NOR53_215
[T] COG0642 Signal transduction histidine kinase.
 
0.999
EED33682.1
[T] COG0642 Signal transduction histidine kinase.
 
0.999
EED32126.1
Hamp domain protein; [NT] COG0840 Methyl-accepting chemotaxis protein.
 
 
 0.998
NOR53_559
Diguanylate cyclaSe/phosphodiesterase with PAS/PAC sensor(s); [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins.
 0.998
NOR53_65
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase; [T] COG2199 FOG: GGDEF domain.
0.998
NOR53_690
Hypothetical protein.
  
 0.998
EED32585.1
Two-component response regulator; [T] COG0784 FOG: CheY-like receiver.
0.997
phoB
Phosphate regulon transcriptional regulatory protein PhoB; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.997
EED32586.1
Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
0.997
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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