STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EED31902.1Conserved hypothetical protein; [K] COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (208 aa)    
Predicted Functional Partners:
EED31528.1
Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
 0.997
EED31903.1
Conserved hypothetical protein TIGR00250; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
  
  
 0.956
gshB
Glutathione synthase; [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the prokaryotic GSH synthase family.
 
   
 0.835
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.793
EED31901.1
[M] COG0810 Periplasmic protein TonB, links inner and outer membranes.
       0.750
metF
[E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
     0.662
sdhD
Succinate dehydrogenase, hydrophobic membrane anchor protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.
   
    0.638
EED31899.1
PAS/PAC sensor signal transduction histidine kinase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
     
 0.632
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.602
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.590
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.