| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED32110.1 | EED32111.1 | NOR53_3396 | NOR53_3212 | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Transcriptional regulator, IclR-family; [K] COG1414 Transcriptional regulator. | 0.773 |
| EED32110.1 | EED32642.1 | NOR53_3396 | NOR53_2206 | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Sensor histidine kinase, putative proline sensor PrlS; [T] COG2205 Osmosensitive K+ channel histidine kinase. | 0.443 |
| EED32110.1 | EED33159.1 | NOR53_3396 | NOR53_1393 | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | SlyX superfamily protein; [S] COG2900 Uncharacterized protein conserved in bacteria. | 0.563 |
| EED32110.1 | EED33192.1 | NOR53_3396 | NOR53_1195 | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Bacterial NAD-glutamate dehydrogenase superfamily protein; [E] COG2902 NAD-specific glutamate dehydrogenase. | 0.480 |
| EED32110.1 | EED33976.1 | NOR53_3396 | NOR53_1370 | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Low molecular weight phosphotyrosine protein phosphatase; [T] COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.440 |
| EED32110.1 | NOR53_658 | NOR53_3396 | NOR53_658 | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | MutT/nudix family protein; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.477 |
| EED32110.1 | nudH | NOR53_3396 | NOR53_3614 | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | (di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.477 |
| EED32110.1 | rpoB | NOR53_3396 | NOR53_223 | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.452 |
| EED32110.1 | rpoC | NOR53_3396 | NOR53_422 | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.498 |
| EED32110.1 | rpoZ | NOR53_3396 | NOR53_3371 | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.464 |
| EED32111.1 | EED32110.1 | NOR53_3212 | NOR53_3396 | Transcriptional regulator, IclR-family; [K] COG1414 Transcriptional regulator. | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.773 |
| EED32642.1 | EED32110.1 | NOR53_2206 | NOR53_3396 | Sensor histidine kinase, putative proline sensor PrlS; [T] COG2205 Osmosensitive K+ channel histidine kinase. | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.443 |
| EED33159.1 | EED32110.1 | NOR53_1393 | NOR53_3396 | SlyX superfamily protein; [S] COG2900 Uncharacterized protein conserved in bacteria. | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.563 |
| EED33192.1 | EED32110.1 | NOR53_1195 | NOR53_3396 | Bacterial NAD-glutamate dehydrogenase superfamily protein; [E] COG2902 NAD-specific glutamate dehydrogenase. | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.480 |
| EED33976.1 | EED32110.1 | NOR53_1370 | NOR53_3396 | Low molecular weight phosphotyrosine protein phosphatase; [T] COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.440 |
| NOR53_658 | EED32110.1 | NOR53_658 | NOR53_3396 | MutT/nudix family protein; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.477 |
| nudH | EED32110.1 | NOR53_3614 | NOR53_3396 | (di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.477 |
| rpoB | EED32110.1 | NOR53_223 | NOR53_3396 | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Histidine triad protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.452 |
| rpoB | rpoC | NOR53_223 | NOR53_422 | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoB | rpoZ | NOR53_223 | NOR53_3371 | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.999 |