Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rfbCdTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa)    
Predicted Functional Partners:
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 0.999
rfbD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.
 
 0.998
rfbB
dTDP-glucose 4,6-dehydratase; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 0.998
NOR53_287
RmlD substrate binding domain superfamily protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.
 
 
 0.977
EED32554.1
Udp-glucose 6-dehydrogenase; [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase.
  
 
 0.946
NOR53_57
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [G] COG0662 Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.930
NOR53_611
Nucleotidyltransferase; [G] COG0448 ADP-glucose pyrophosphorylase.
  
 
 0.912
EED33978.1
Putative UDP-glucose lipid carrier transferase; [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
 
 0.861
NOR53_47
Glycosyl transferase, family 2; [M] COG0438 Glycosyltransferase.
 
  
 0.861
EED32232.1
Transferase hexapeptide repeat containing protein.
  
 
 0.788
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.