Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
speB_2Agmatinase; [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. (314 aa)    
Predicted Functional Partners:
argD
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 0.943
putA_1
Bifunctional PutA protein; [C] COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase.
  
 
 0.850
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
     
 0.752
EED33695.1
Putative aminotransferase class III (putative 4-aminobutyrate aminotransferase); [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.695
ldcC
[E] COG1982 Arginine/lysine/ornithine decarboxylases.
 
  
 0.676
leuS
[J] COG0060 Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.671
EED31825.1
Methyltransferase domain family protein; [E] COG0421 Spermidine synthase.
  
 
 0.667
EED32267.1
[E] COG0174 Glutamine synthetase.
  
  
 0.631
EED31784.1
Aminotransferase, class III; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
  0.620
argA_1
Amino-acid N-acetyltransferase; [E] COG1246 N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family. ArgA subfamily.
  
 
 0.617
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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