mutY protein (gamma proteobacterium NOR53) - STRING interaction network

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Score

mutY

A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (359 aa)

Predicted Functional Partners:

sfsA

0.936

dnaN

0.899

EED32150.1

0.829

EED31933.1

0.787

xth

0.787

hisB

0.657

polA

0.612

radA

0.602

hisH

0.596

EED33840.1

0.593

Your Current Organism:

gamma proteobacterium NOR53

NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EED31933.1	dnaN	NOR53_3316	NOR53_3590	[L] COG0708 Exonuclease III.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.832
EED31933.1	mutY	NOR53_3316	NOR53_3424	[L] COG0708 Exonuclease III.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.787
EED31933.1	polA	NOR53_3316	NOR53_3282	[L] COG0708 Exonuclease III.	DNA polymerase I superfamily protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.781
EED32150.1	hisB	NOR53_3101	NOR53_3264	Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.	[E] COG0131 Imidazoleglycerol-phosphate dehydratase.	0.657
EED32150.1	hisH	NOR53_3101	NOR53_3503	Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.	Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.542
EED32150.1	mutY	NOR53_3101	NOR53_3424	Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.829
EED33840.1	mutY	NOR53_1666	NOR53_3424	Mutator MutT protein; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.593
dnaN	EED31933.1	NOR53_3590	NOR53_3316	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	[L] COG0708 Exonuclease III.	0.832
dnaN	mutY	NOR53_3590	NOR53_3424	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.899
dnaN	polA	NOR53_3590	NOR53_3282	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I superfamily protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.995
dnaN	xth	NOR53_3590	NOR53_846	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	[L] COG0708 Exonuclease III.	0.832
hisB	EED32150.1	NOR53_3264	NOR53_3101	[E] COG0131 Imidazoleglycerol-phosphate dehydratase.	Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.	0.657
hisB	hisH	NOR53_3264	NOR53_3503	[E] COG0131 Imidazoleglycerol-phosphate dehydratase.	Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.998
hisB	mutY	NOR53_3264	NOR53_3424	[E] COG0131 Imidazoleglycerol-phosphate dehydratase.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.657
hisH	EED32150.1	NOR53_3503	NOR53_3101	Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.	0.542
hisH	hisB	NOR53_3503	NOR53_3264	Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	[E] COG0131 Imidazoleglycerol-phosphate dehydratase.	0.998
hisH	mutY	NOR53_3503	NOR53_3424	Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.596
mutY	EED31933.1	NOR53_3424	NOR53_3316	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	[L] COG0708 Exonuclease III.	0.787
mutY	EED32150.1	NOR53_3424	NOR53_3101	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.	0.829
mutY	EED33840.1	NOR53_3424	NOR53_1666	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Mutator MutT protein; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.	0.593