STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsPPhosphoenolpyruvate-protein phosphotransferase; [G] COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (756 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr; [G] COG1925 Phosphotransferase system, HPr-related proteins.
  
 
 0.988
nudH
(di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
  
 
  0.864
NOR53_694
Nitrogen regulatory protein (Enzyme IIA-NTR); [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
  
   
 0.772
EED32586.1
Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
   
  0.740
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.675
EED34033.1
CheB methylesterase/CheR methyltransferase; [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
  
 
  0.671
EED32335.1
Hypothetical protein; [T] COG2200 FOG: EAL domain; pas:ggdef.
    
  0.614
NOR53_724
Hypothetical protein; [T] COG2200 FOG: EAL domain; pas:ggdef.
    
  0.614
NOR53_559
Diguanylate cyclaSe/phosphodiesterase with PAS/PAC sensor(s); [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins.
    
  0.584
EED31870.1
HAD-superfamily subfamily IB hydrolase; [E] COG0560 Phosphoserine phosphatase.
       0.580
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.