| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED32186.1 | EED32728.1 | NOR53_3054 | NOR53_2076 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | 0.647 |
| EED32186.1 | EED32973.1 | NOR53_3054 | NOR53_1808 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | [F] COG1051 ADP-ribose pyrophosphatase. | 0.647 |
| EED32186.1 | ald | NOR53_3054 | NOR53_2266 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | Alanine dehydrogenase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit; Belongs to the AlaDH/PNT family. | 0.491 |
| EED32186.1 | ilvC | NOR53_3054 | NOR53_303 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.465 |
| EED32186.1 | nadD | NOR53_3054 | NOR53_2825 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.647 |
| EED32186.1 | nadE | NOR53_3054 | NOR53_149 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.746 |
| EED32186.1 | nadK | NOR53_3054 | NOR53_2386 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.853 |
| EED32186.1 | pntA | NOR53_3054 | NOR53_3475 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD(P) transhydrogenase, alpha subunit; [E] COG0686 Alanine dehydrogenase. | 0.998 |
| EED32186.1 | pntB | NOR53_3054 | NOR53_3022 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
| EED32186.1 | rpoC | NOR53_3054 | NOR53_422 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.593 |
| EED32728.1 | EED32186.1 | NOR53_2076 | NOR53_3054 | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.647 |
| EED32728.1 | EED32973.1 | NOR53_2076 | NOR53_1808 | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | [F] COG1051 ADP-ribose pyrophosphatase. | 0.668 |
| EED32728.1 | nadD | NOR53_2076 | NOR53_2825 | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.649 |
| EED32728.1 | nadE | NOR53_2076 | NOR53_149 | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.739 |
| EED32728.1 | nadK | NOR53_2076 | NOR53_2386 | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.647 |
| EED32728.1 | pntA | NOR53_2076 | NOR53_3475 | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | NAD(P) transhydrogenase, alpha subunit; [E] COG0686 Alanine dehydrogenase. | 0.647 |
| EED32728.1 | pntB | NOR53_2076 | NOR53_3022 | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.650 |
| EED32973.1 | EED32186.1 | NOR53_1808 | NOR53_3054 | [F] COG1051 ADP-ribose pyrophosphatase. | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.647 |
| EED32973.1 | EED32728.1 | NOR53_1808 | NOR53_2076 | [F] COG1051 ADP-ribose pyrophosphatase. | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | 0.668 |
| EED32973.1 | ald | NOR53_1808 | NOR53_2266 | [F] COG1051 ADP-ribose pyrophosphatase. | Alanine dehydrogenase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit; Belongs to the AlaDH/PNT family. | 0.506 |