| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31528.1 | EED32140.1 | NOR53_2782 | NOR53_3487 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | 0.692 |
| EED31528.1 | EED32586.1 | NOR53_2782 | NOR53_2381 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. | 0.767 |
| EED31528.1 | NOR53_60 | NOR53_2782 | NOR53_60 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.793 |
| EED31528.1 | metH | NOR53_2782 | NOR53_1222 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.688 |
| EED31528.1 | ribB | NOR53_2782 | NOR53_1489 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.793 |
| EED31664.1 | EED32140.1 | NOR53_3171 | NOR53_3487 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | 0.540 |
| EED31664.1 | NOR53_376 | NOR53_3171 | NOR53_376 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.714 |
| EED31664.1 | metH | NOR53_3171 | NOR53_1222 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.664 |
| EED31664.1 | nadE | NOR53_3171 | NOR53_149 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.690 |
| EED32139.1 | EED32140.1 | NOR53_3560 | NOR53_3487 | Conserved hypothetical protein. | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | 0.620 |
| EED32140.1 | EED31528.1 | NOR53_3487 | NOR53_2782 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.692 |
| EED32140.1 | EED31664.1 | NOR53_3487 | NOR53_3171 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.540 |
| EED32140.1 | EED32139.1 | NOR53_3487 | NOR53_3560 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Conserved hypothetical protein. | 0.620 |
| EED32140.1 | EED32586.1 | NOR53_3487 | NOR53_2381 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. | 0.536 |
| EED32140.1 | NOR53_376 | NOR53_3487 | NOR53_376 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.599 |
| EED32140.1 | NOR53_60 | NOR53_3487 | NOR53_60 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.551 |
| EED32140.1 | cinA | NOR53_3487 | NOR53_194 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.614 |
| EED32140.1 | metH | NOR53_3487 | NOR53_1222 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.711 |
| EED32140.1 | nadE | NOR53_3487 | NOR53_149 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.657 |
| EED32140.1 | ribB | NOR53_3487 | NOR53_1489 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.551 |