| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31528.1 | EED32140.1 | NOR53_2782 | NOR53_3487 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | 0.680 |
| EED31528.1 | EED32335.1 | NOR53_2782 | NOR53_2979 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; [T] COG2200 FOG: EAL domain; pas:ggdef. | 0.716 |
| EED31528.1 | EED32586.1 | NOR53_2782 | NOR53_2381 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. | 0.733 |
| EED31528.1 | guaA | NOR53_2782 | NOR53_772 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.621 |
| EED31528.1 | metH | NOR53_2782 | NOR53_1222 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.552 |
| EED31664.1 | EED32140.1 | NOR53_3171 | NOR53_3487 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | 0.641 |
| EED31664.1 | NOR53_376 | NOR53_3171 | NOR53_376 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.611 |
| EED31664.1 | metH | NOR53_3171 | NOR53_1222 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.773 |
| EED31664.1 | nadE | NOR53_3171 | NOR53_149 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.693 |
| EED32139.1 | EED32140.1 | NOR53_3560 | NOR53_3487 | Conserved hypothetical protein. | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | 0.620 |
| EED32140.1 | EED31528.1 | NOR53_3487 | NOR53_2782 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.680 |
| EED32140.1 | EED31664.1 | NOR53_3487 | NOR53_3171 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.641 |
| EED32140.1 | EED32139.1 | NOR53_3487 | NOR53_3560 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Conserved hypothetical protein. | 0.620 |
| EED32140.1 | EED32335.1 | NOR53_3487 | NOR53_2979 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Hypothetical protein; [T] COG2200 FOG: EAL domain; pas:ggdef. | 0.573 |
| EED32140.1 | EED32586.1 | NOR53_3487 | NOR53_2381 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. | 0.644 |
| EED32140.1 | NOR53_376 | NOR53_3487 | NOR53_376 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.685 |
| EED32140.1 | cinA | NOR53_3487 | NOR53_194 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.716 |
| EED32140.1 | guaA | NOR53_3487 | NOR53_772 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.597 |
| EED32140.1 | metH | NOR53_3487 | NOR53_1222 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.697 |
| EED32140.1 | nadE | NOR53_3487 | NOR53_149 | Nudix hydrolase; [F] COG1051 ADP-ribose pyrophosphatase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.742 |