Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED31600.1[H] COG1239 Mg-chelatase subunit ChlI. (496 aa)    
Predicted Functional Partners:
dprA
Peptide deformylase, DNA processing protein; [LU] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
 
 
 0.829
EED32237.1
Phosphoribosyltransferase; [R] COG1040 Predicted amidophosphoribosyltransferases.
 
  
 0.806
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
   
 0.624
EED33756.1
Competence protein ComEA helix-hairpin-helix repeat region; [K] COG2183 Transcriptional accessory protein.
  
  
 0.613
EED33861.1
Conserved hypothetical protein TIGR00252; [L] COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.
 
  
 0.581
NOR53_692
DNA internalization-related competence protein ComEC/Rec2; [R] COG0658 Predicted membrane metal-binding protein.
  
  
 0.563
EED32126.1
Hamp domain protein; [NT] COG0840 Methyl-accepting chemotaxis protein.
  
    0.560
EED31599.1
[S] COG2960 Uncharacterized protein conserved in bacteria.
       0.530
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
     0.524
secF
Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
     0.508
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.