Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
caiBL-carnitine dehydrogenase; [C] COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family. (402 aa)    
Predicted Functional Partners:
EED31778.1
[I] COG1960 Acyl-CoA dehydrogenases.
 
  0.917
EED31776.1
Hypothetical protein; [LKJ] COG0513 Superfamily II DNA and RNA helicases; signal peptide.
       0.714
EED33454.1
Putative Phosphate acetyl/butyryl transferase subfamily; [C] COG0281 Malic enzyme.
     
 0.661
NOR53_376
Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.618
EED32900.1
[I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).
    
 0.593
EED31664.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
     
 0.572
oadA
Oxaloacetate decarboxylase alpha subunit; [I] COG0511 Biotin carboxyl carrier protein.
     
  0.540
EED31779.1
Transcriptional regulator, LuxR family; [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
       0.535
sucD
succinyl-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
  0.518
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
  0.505
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.