Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED31830.1[GEPR] COG0477 Permeases of the major facilitator superfamily. (386 aa)    
Predicted Functional Partners:
EED31829.1
Dehydrogenase/reductase sdr family member 4; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
       0.605
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
       0.603
hom
[E] COG0460 Homoserine dehydrogenase.
   
  0.552
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.527
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
      0.494
EED33765.1
P-protein; [E] COG1605 Chorismate mutase.
   
 
 0.489
EED31772.1
Acyltransferase family protein; [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
     
  0.458
EED31833.1
Putative 4-coumarate--CoA ligase 2; [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
    
  0.455
EED33704.1
[MU] COG1538 Outer membrane protein.
  
  0.451
EED31832.1
Hypothetical protein; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold.
       0.442
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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