| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31528.1 | EED31694.1 | NOR53_2782 | NOR53_3272 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | 0.537 |
| EED31528.1 | EED32130.1 | NOR53_2782 | NOR53_3118 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Selenide, water dikinase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | 0.420 |
| EED31528.1 | NOR53_60 | NOR53_2782 | NOR53_60 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.774 |
| EED31528.1 | metH | NOR53_2782 | NOR53_1222 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.552 |
| EED31528.1 | ribB | NOR53_2782 | NOR53_1489 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.774 |
| EED31528.1 | trx | NOR53_2782 | NOR53_3688 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thioredoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | 0.731 |
| EED31528.1 | trxB | NOR53_2782 | NOR53_688 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thioredoxin-disulfide reductase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.509 |
| EED31694.1 | EED31528.1 | NOR53_3272 | NOR53_2782 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.537 |
| EED31694.1 | EED32130.1 | NOR53_3272 | NOR53_3118 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Selenide, water dikinase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | 0.734 |
| EED31694.1 | NOR53_60 | NOR53_3272 | NOR53_60 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.884 |
| EED31694.1 | cysH | NOR53_3272 | NOR53_3154 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Phosphoadenosine-phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.757 |
| EED31694.1 | merA | NOR53_3272 | NOR53_3056 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Mercuric reductase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.710 |
| EED31694.1 | metH | NOR53_3272 | NOR53_1222 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.527 |
| EED31694.1 | ribB | NOR53_3272 | NOR53_1489 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.884 |
| EED31694.1 | trx | NOR53_3272 | NOR53_3688 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Thioredoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | 0.719 |
| EED31694.1 | trxB | NOR53_3272 | NOR53_688 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | Thioredoxin-disulfide reductase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.762 |
| EED32130.1 | EED31528.1 | NOR53_3118 | NOR53_2782 | Selenide, water dikinase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.420 |
| EED32130.1 | EED31694.1 | NOR53_3118 | NOR53_3272 | Selenide, water dikinase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | 0.734 |
| EED32130.1 | merA | NOR53_3118 | NOR53_3056 | Selenide, water dikinase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | Mercuric reductase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.617 |
| EED32130.1 | trx | NOR53_3118 | NOR53_3688 | Selenide, water dikinase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | Thioredoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | 0.836 |