Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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ntrCNitrogen regulation protein NR (I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (472 aa)    
Predicted Functional Partners:
glnL
Nitrogen regulation protein NR (II); [T] COG0642 Signal transduction histidine kinase.
 0.981
EED31684.1
Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase.
  
 0.876
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.843
EED34033.1
CheB methylesterase/CheR methyltransferase; [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
  
 0.836
NOR53_215
[T] COG0642 Signal transduction histidine kinase.
  
 0.822
trmL
RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
       0.773
EED33682.1
[T] COG0642 Signal transduction histidine kinase.
  
 0.754
EED31395.1
Sensor histidine kinase/response regulator; [T] COG0642 Signal transduction histidine kinase.
 
 
 0.687
EED31642.1
Hdod domain family protein; [T] COG1639 Predicted signal transduction protein.
  
  0.683
NOR53_141
Surface presentation of antigens protein; [N] COG1868 Flagellar motor switch protein.
  
 
 0.653
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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