Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
NOR53_402Peptidase M16 domain protein; [O] COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like; Belongs to the peptidase M16 family. (958 aa)    
Predicted Functional Partners:
NOR53_99
Permease, PerM family; [R] COG0628 Predicted permease.
       0.792
NOR53_165
Conserved hypothetical protein; [O] COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.
       0.783
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 
  0.725
NOR53_214
Molybdopterin converting factor, subunit 1; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
 
     0.664
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
    
  0.583
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
     
  0.541
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
  0.523
EED32518.1
Transporter; [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.
     
  0.508
EED32517.1
Von Willebrand factor, type A; [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.
     
  0.508
EED33197.1
TPR repeat-containing protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
     
  0.508
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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