Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOR53_414Transcriptional regulator, MarR family; [K] COG1846 Transcriptional regulators. (158 aa)    
Predicted Functional Partners:
maiA_2
Maleylacetoacetate isomerase; [O] COG0625 Glutathione S-transferase.
 
     0.827
hppD
[ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.
 
    0.719
NOR53_7
[Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
 
     0.667
hmgA
[Q] COG3508 Homogentisate 1,2-dioxygenase.
     
 0.658
NOR53_188
[E] COG3186 Phenylalanine-4-hydroxylase.
    
  0.655
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
  
 0.618
glnS
[J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases.
   
    0.617
lepB
[U] COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
   
    0.549
rplY
Ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
   
    0.547
EED32422.1
2-oxoacid:ferredoxin/flavodoxin oxidoreductase, gamma subunit domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
  
  
 0.543
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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