Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOR53_446[V] COG1680 Beta-lactamase class C and other penicillin binding proteins. (542 aa)    
Predicted Functional Partners:
EED33344.1
[V] COG1680 Beta-lactamase class C and other penicillin binding proteins.
  
     0.765
EED31806.1
[V] COG1680 Beta-lactamase class C and other penicillin binding proteins.
  
     0.749
NOR53_469
Conserved hypothetical protein.
       0.741
NOR53_464
Hypothetical protein; [F] COG1457 Purine-cytosine permease and related proteins; putative permease for cytosine/purinesuracil, thiamine, allantoin taxon:342610.
 
     0.576
NOR53_557
[CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.544
NOR53_468
[S] COG3535 Uncharacterized conserved protein.
       0.518
NOR53_493
Hydantoinase/oxoprolinase family protein; [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit.
       0.518
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.469
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
       0.461
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
 0.451
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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