STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOR53_449Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits. (570 aa)    
Predicted Functional Partners:
hsdM
[V] COG0286 Type I restriction-modification system methyltransferase subunit.
 
 
 0.999
NOR53_461
EcoEI R C-terminal domain protein; [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
 
 
 0.995
NOR53_596
Conserved hypothetical protein.
 
  
 0.986
EED33277.1
Sea11; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
  
 0.916
atpF
ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). Belongs to the ATPase B chain family.
    
 
 0.533
EED33275.1
Hypothetical protein; [V] COG1002 Type II restriction enzyme, methylase subunits.
   
  
 0.514
polA
DNA polymerase I superfamily protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.508
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
   0.462
EED31304.1
Type III restriction enzyme, res subunit; [KL] COG1061 DNA or RNA helicases of superfamily II.
 
    0.402
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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