STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsdM[V] COG0286 Type I restriction-modification system methyltransferase subunit. (489 aa)    
Predicted Functional Partners:
NOR53_449
Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.
 
 
 0.999
NOR53_461
EcoEI R C-terminal domain protein; [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
 
 
 0.994
EED33277.1
Sea11; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
 
 0.989
NOR53_596
Conserved hypothetical protein.
 
  
 0.962
NOR53_922
[V] COG1715 Restriction endonuclease.
 
  
 0.629
EED31309.1
Conserved hypothetical protein.
  
  
 0.613
EED33275.1
Hypothetical protein; [V] COG1002 Type II restriction enzyme, methylase subunits.
  
    0.578
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
 0.490
EED31304.1
Type III restriction enzyme, res subunit; [KL] COG1061 DNA or RNA helicases of superfamily II.
 
   
 0.474
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.464
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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