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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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from curated databases
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
hsdM[V] COG0286 Type I restriction-modification system methyltransferase subunit. (489 aa)    
Predicted Functional Partners:
NOR53_449
Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.
 
 0.999
NOR53_461
EcoEI R C-terminal domain protein; [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
 
 0.998
NOR53_596
Conserved hypothetical protein.
 
  
 0.932
EED33277.1
Sea11; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
  
 0.912
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
  0.811
atpF
ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). Belongs to the ATPase B chain family.
   
 0.694
NOR53_922
[V] COG1715 Restriction endonuclease.
 
  
 0.687
EED31309.1
Conserved hypothetical protein.
  
  
 0.624
EED33275.1
Hypothetical protein; [V] COG1002 Type II restriction enzyme, methylase subunits.
  
    0.584
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
     
 0.515
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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