| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31913.1 | NOR53_509 | NOR53_3554 | NOR53_509 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | [S] COG1981 Predicted membrane protein. | 0.631 |
| EED31913.1 | hemF | NOR53_3554 | NOR53_3018 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.641 |
| EED31913.1 | hemN | NOR53_3554 | NOR53_685 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Oxygen-independent coproporphyrinogen III oxidase; [KB] COG1243 Histone acetyltransferase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.655 |
| EED32382.1 | NOR53_509 | NOR53_1101 | NOR53_509 | [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | [S] COG1981 Predicted membrane protein. | 0.608 |
| EED32382.1 | hemF | NOR53_1101 | NOR53_3018 | [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.625 |
| EED32382.1 | hemN | NOR53_1101 | NOR53_685 | [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Oxygen-independent coproporphyrinogen III oxidase; [KB] COG1243 Histone acetyltransferase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.659 |
| NOR53_509 | EED31913.1 | NOR53_509 | NOR53_3554 | [S] COG1981 Predicted membrane protein. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.631 |
| NOR53_509 | EED32382.1 | NOR53_509 | NOR53_1101 | [S] COG1981 Predicted membrane protein. | [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.608 |
| NOR53_509 | NOR53_661 | NOR53_509 | NOR53_661 | [S] COG1981 Predicted membrane protein. | Cl- channel, voltage-gated family protein; [P] COG0038 Chloride channel protein EriC. | 0.814 |
| NOR53_509 | argC | NOR53_509 | NOR53_573 | [S] COG1981 Predicted membrane protein. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.594 |
| NOR53_509 | chlD | NOR53_509 | NOR53_1137 | [S] COG1981 Predicted membrane protein. | Protoporphyrin IX Magnesium chelatase subunit ChlD; [H] COG1239 Mg-chelatase subunit ChlI. | 0.699 |
| NOR53_509 | hemB | NOR53_509 | NOR53_584 | [S] COG1981 Predicted membrane protein. | [H] COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.622 |
| NOR53_509 | hemF | NOR53_509 | NOR53_3018 | [S] COG1981 Predicted membrane protein. | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.783 |
| NOR53_509 | hemH | NOR53_509 | NOR53_51 | [S] COG1981 Predicted membrane protein. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.763 |
| NOR53_509 | hemL | NOR53_509 | NOR53_490 | [S] COG1981 Predicted membrane protein. | Glutamate-1-semialdehyde-2,1-aminomutase; [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases. | 0.599 |
| NOR53_509 | hemN | NOR53_509 | NOR53_685 | [S] COG1981 Predicted membrane protein. | Oxygen-independent coproporphyrinogen III oxidase; [KB] COG1243 Histone acetyltransferase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.678 |
| NOR53_661 | NOR53_509 | NOR53_661 | NOR53_509 | Cl- channel, voltage-gated family protein; [P] COG0038 Chloride channel protein EriC. | [S] COG1981 Predicted membrane protein. | 0.814 |
| NOR53_661 | argC | NOR53_661 | NOR53_573 | Cl- channel, voltage-gated family protein; [P] COG0038 Chloride channel protein EriC. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.598 |
| NOR53_661 | hemB | NOR53_661 | NOR53_584 | Cl- channel, voltage-gated family protein; [P] COG0038 Chloride channel protein EriC. | [H] COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.517 |
| NOR53_661 | hemL | NOR53_661 | NOR53_490 | Cl- channel, voltage-gated family protein; [P] COG0038 Chloride channel protein EriC. | Glutamate-1-semialdehyde-2,1-aminomutase; [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases. | 0.595 |