Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOR53_530Cell division protein FtsA; [G] COG0524 Sugar kinases, ribokinase family. (333 aa)    
Predicted Functional Partners:
NOR53_57
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [G] COG0662 Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.814
NOR53_221
Superoxide dismutase (Fe); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 0.809
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.787
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.787
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; [R] COG1411 Uncharacterized protein related to proFAR isomerase (HisA).
  
    0.724
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.701
purB
Adenylosuccinate lyase; [C] COG0114 Fumarase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.691
EED33441.1
Khg/kdpg aldolase; [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.
  
 
 0.647
EED32601.1
Inositol-1-monophosphatase; [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.
 
 
 0.644
EED32558.1
[KG] COG1940 Transcriptional regulator/sugar kinase.
 
 
 0.640
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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