Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
nhaANa+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (391 aa)    
Predicted Functional Partners:
EED32656.1
Conserved hypothetical protein.
   
    0.833
NOR53_603
Oxidoreductase htatip2; [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases.
       0.794
EED31780.1
Glutathione-regulated potassium-efflux system protein KefC; [P] COG1226 Kef-type K+ transport systems, predicted NAD-binding component; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
 0.600
EED32402.1
Manganese/divalent cation transport protein (nramp); [ER] COG0591 Na+/proline symporter.
     
 0.587
nhaB
Excinuclease ABC, C subunit; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
      
 0.578
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
      
 0.578
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
      
 0.578
NOR53_636
Alcohol dehydrogenase (acceptor); [S] COG1520 FOG: WD40-like repeat.
     
 0.543
NOR53_671
[E] COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases.
       0.522
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  
 0.487
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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