Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dsbDThiol:disulfide interchange protein DsbD; [O] COG0785 Cytochrome c biogenesis protein. (582 aa)    
Predicted Functional Partners:
EED32577.1
Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
 
 0.941
ccmG
Cytochrome C biogenesis protein CcmG; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 
 0.936
NOR53_673
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 
 0.871
NOR53_677
Redoxin superfamily protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 
 0.871
NOR53_181
[O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.
    
 
 0.802
msrA-2
Peptide methionine sulfoxide reductase MsrA 2; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
    
 
 0.715
msrA
methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
    
 
 0.715
EED33735.1
Conserved hypothetical protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 
 0.691
groS
Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
     
 0.669
accB
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
     
 0.628
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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