Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOR53_567Amidohydrolase family protein; [R] COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold. (410 aa)    
Predicted Functional Partners:
NOR53_560
Retinol dehydrogenase 12; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 
  0.785
EED32850.1
Reductive dehalogenase; [C] COG1600 Uncharacterized Fe-S protein.
    
  0.596
NOR53_544
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
       0.520
ligK_2
4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; [H] COG0684 Demethylmenaquinone methyltransferase.
 
  
 0.518
ligK_1
4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; [H] COG0684 Demethylmenaquinone methyltransferase.
 
  
 0.517
NOR53_593
Conserved hypothetical protein.
       0.516
paaF
phenylacetate-CoA ligase; [H] COG1541 Coenzyme F390 synthetase.
 
     0.485
NOR53_578
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
       0.472
adeC
[F] COG1001 Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
       0.472
fldA_2
FldA protein; [S] COG2828 Uncharacterized protein conserved in bacteria.
 
  
  0.421
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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