| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NOR53_119 | NOR53_570 | NOR53_119 | NOR53_570 | [T] COG1956 GAF domain-containing protein. | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | 0.511 |
| NOR53_119 | metC | NOR53_119 | NOR53_2129 | [T] COG1956 GAF domain-containing protein. | [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.534 |
| NOR53_119 | metH | NOR53_119 | NOR53_1222 | [T] COG1956 GAF domain-containing protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.739 |
| NOR53_119 | metK | NOR53_119 | NOR53_2915 | [T] COG1956 GAF domain-containing protein. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.647 |
| NOR53_119 | metY | NOR53_119 | NOR53_940 | [T] COG1956 GAF domain-containing protein. | O-acetylhomoserine sulfhydrylase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.649 |
| NOR53_119 | metZ | NOR53_119 | NOR53_2241 | [T] COG1956 GAF domain-containing protein. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.534 |
| NOR53_570 | NOR53_119 | NOR53_570 | NOR53_119 | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | [T] COG1956 GAF domain-containing protein. | 0.511 |
| NOR53_570 | NOR53_600 | NOR53_570 | NOR53_600 | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | enoyl-CoA hydratase/isomerase family protein; [H] COG0447 Dihydroxynaphthoic acid synthase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.773 |
| NOR53_570 | NOR53_601 | NOR53_570 | NOR53_601 | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | Glycosyl hydrolase, BNR repeat-containing protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.520 |
| NOR53_570 | cysM | NOR53_570 | NOR53_755 | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | Cysteine synthase B; [E] COG0498 Threonine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.515 |
| NOR53_570 | fur | NOR53_570 | NOR53_336 | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | [P] COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family. | 0.727 |
| NOR53_570 | metC | NOR53_570 | NOR53_2129 | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.579 |
| NOR53_570 | metH | NOR53_570 | NOR53_1222 | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.739 |
| NOR53_570 | metK | NOR53_570 | NOR53_2915 | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.537 |
| NOR53_570 | metY | NOR53_570 | NOR53_940 | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | O-acetylhomoserine sulfhydrylase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.929 |
| NOR53_570 | metZ | NOR53_570 | NOR53_2241 | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.814 |
| NOR53_600 | NOR53_570 | NOR53_600 | NOR53_570 | enoyl-CoA hydratase/isomerase family protein; [H] COG0447 Dihydroxynaphthoic acid synthase; Belongs to the enoyl-CoA hydratase/isomerase family. | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | 0.773 |
| NOR53_600 | NOR53_601 | NOR53_600 | NOR53_601 | enoyl-CoA hydratase/isomerase family protein; [H] COG0447 Dihydroxynaphthoic acid synthase; Belongs to the enoyl-CoA hydratase/isomerase family. | Glycosyl hydrolase, BNR repeat-containing protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.520 |
| NOR53_600 | metH | NOR53_600 | NOR53_1222 | enoyl-CoA hydratase/isomerase family protein; [H] COG0447 Dihydroxynaphthoic acid synthase; Belongs to the enoyl-CoA hydratase/isomerase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.529 |
| NOR53_601 | NOR53_570 | NOR53_601 | NOR53_570 | Glycosyl hydrolase, BNR repeat-containing protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). | 0.520 |