Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOR53_570Protein YccU; [C] COG1042 Acyl-CoA synthetase (NDP forming). (142 aa)    
Predicted Functional Partners:
metY
O-acetylhomoserine sulfhydrylase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
   
  0.929
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
   
  0.814
NOR53_600
enoyl-CoA hydratase/isomerase family protein; [H] COG0447 Dihydroxynaphthoic acid synthase; Belongs to the enoyl-CoA hydratase/isomerase family.
       0.773
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.739
fur
[P] COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
  
    0.727
metC
[E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
 
   
  0.579
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
  0.537
NOR53_601
Glycosyl hydrolase, BNR repeat-containing protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
       0.520
cysM
Cysteine synthase B; [E] COG0498 Threonine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.515
NOR53_119
[T] COG1956 GAF domain-containing protein.
     
  0.511
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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