| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31528.1 | NOR53_60 | NOR53_2782 | NOR53_60 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.793 |
| EED31528.1 | folE_1 | NOR53_2782 | NOR53_2163 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | [H] COG0302 GTP cyclohydrolase I. | 0.746 |
| EED31528.1 | folE_2 | NOR53_2782 | NOR53_1545 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | [H] COG0302 GTP cyclohydrolase I. | 0.746 |
| EED31528.1 | folK_1 | NOR53_2782 | NOR53_2432 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.739 |
| EED31528.1 | folK_2 | NOR53_2782 | NOR53_586 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.739 |
| EED31528.1 | ribB | NOR53_2782 | NOR53_1489 | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.793 |
| NOR53_60 | EED31528.1 | NOR53_60 | NOR53_2782 | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Putative ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.793 |
| NOR53_60 | folC | NOR53_60 | NOR53_1911 | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase; Belongs to the folylpolyglutamate synthase family. | 0.446 |
| NOR53_60 | folE_1 | NOR53_60 | NOR53_2163 | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | [H] COG0302 GTP cyclohydrolase I. | 0.708 |
| NOR53_60 | folE_2 | NOR53_60 | NOR53_1545 | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | [H] COG0302 GTP cyclohydrolase I. | 0.708 |
| NOR53_60 | folK_1 | NOR53_60 | NOR53_2432 | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.735 |
| NOR53_60 | folK_2 | NOR53_60 | NOR53_586 | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.735 |
| NOR53_60 | ribB | NOR53_60 | NOR53_1489 | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.696 |
| folB | folC | NOR53_476 | NOR53_1911 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase; Belongs to the folylpolyglutamate synthase family. | 0.895 |
| folB | folE_1 | NOR53_476 | NOR53_2163 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | [H] COG0302 GTP cyclohydrolase I. | 0.930 |
| folB | folE_2 | NOR53_476 | NOR53_1545 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | [H] COG0302 GTP cyclohydrolase I. | 0.941 |
| folB | folK_1 | NOR53_476 | NOR53_2432 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.990 |
| folB | folK_2 | NOR53_476 | NOR53_586 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.996 |
| folB | folP | NOR53_476 | NOR53_2427 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | [H] COG0294 Dihydropteroate synthase and related enzymes. | 0.989 |
| folB | gcp | NOR53_476 | NOR53_485 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.822 |