STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folK_22-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (167 aa)    
Predicted Functional Partners:
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.994
folP
[H] COG0294 Dihydropteroate synthase and related enzymes.
 
 
 0.990
folE_1
[H] COG0302 GTP cyclohydrolase I.
 
  
 0.841
folE_2
[H] COG0302 GTP cyclohydrolase I.
 
  
 0.836
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.815
NOR53_60
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
    
 0.815
gcp
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
       0.799
folC
[M] COG0769 UDP-N-acetylmuramyl tripeptide synthase; Belongs to the folylpolyglutamate synthase family.
 
 
 0.743
folK_1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
  
  
 
0.663
birA
biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
  
 0.595
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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