Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
erpAHesB/YadR/YfhF; Required for insertion of 4Fe-4S clusters for at least IspG. (117 aa)    
Predicted Functional Partners:
EED32710.1
Glycine cleavage T protein; [R] COG0354 Predicted aminomethyltransferase related to GcvT.
 
 0.913
yhgI
IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.907
EED32603.1
Cysteine desulfurase; [R] COG1103 Archaea-specific pyridoxal phosphate-dependent enzymes.
 
 
 0.879
dndA
Cysteine desulfurase DndA; [E] COG0520 Selenocysteine lyase.
 
 
 0.876
EED31526.1
[O] COG0695 Glutaredoxin and related proteins; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 0.809
EED32047.1
DnaJ-domain containing protein; [O] COG2214 DnaJ-class molecular chaperone.
  
 
 0.798
EED32850.1
Reductive dehalogenase; [C] COG1600 Uncharacterized Fe-S protein.
  
 0.734
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.725
NOR53_836
ParA family protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
 
 0.725
sufD
FeS assembly protein SufD; [O] COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
  
 0.685
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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