Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
htrA[O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (480 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
    
 0.741
NOR53_554
Hypothetical protein.
       0.697
EED32715.1
Anti-sigma factor MucA; [T] COG3073 Negative regulator of sigma E activity.
  
 
 0.657
lepB
[U] COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
 
  
 0.647
NOR53_465
Phosphate-selective porin, OprO/OprP family; [P] COG3746 Phosphate-selective porin.
       0.595
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
   0.503
rplY
Ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
 
 
   0.452
EED33331.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
    
  0.444
EED32755.1
PspC domain family protein; [KT] COG1983 Putative stress-responsive transcriptional regulator.
   
  
 0.436
EED33977.1
Serine protease; [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
  
     0.432
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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