Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trxBThioredoxin-disulfide reductase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (320 aa)    
Predicted Functional Partners:
trx
Thioredoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
 0.998
NOR53_237
Thioredoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 0.916
EED32130.1
Selenide, water dikinase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit.
    
 0.890
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.884
EED32850.1
Reductive dehalogenase; [C] COG1600 Uncharacterized Fe-S protein.
   
 0.854
NOR53_515
Ferredoxin; [C] COG2871 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF.
   
 0.789
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
    
  0.768
ccmG
Cytochrome C biogenesis protein CcmG; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.744
NOR53_673
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.744
NOR53_677
Redoxin superfamily protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.744
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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