Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NOR53_7[Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (330 aa)    
Predicted Functional Partners:
maiA_2
Maleylacetoacetate isomerase; [O] COG0625 Glutathione S-transferase.
 
 
 0.973
hmgA
[Q] COG3508 Homogentisate 1,2-dioxygenase.
 
  
 0.959
hppD
[ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.
 
  
 0.828
NOR53_414
Transcriptional regulator, MarR family; [K] COG1846 Transcriptional regulators.
 
     0.667
EED33374.1
Conserved hypothetical protein; [E] COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases.
 
  
  0.658
NOR53_376
Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
  0.614
NOR53_188
[E] COG3186 Phenylalanine-4-hydroxylase.
 
  
 0.550
sdhD
Succinate dehydrogenase, hydrophobic membrane anchor protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.
   
 
  0.540
sdhC
[C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
   
 
  0.539
mhbB
Fumarylpyruvate hydrolase; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
     
  0.531
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (18%) [HD]