Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NOR53_721[P] COG1629 Outer membrane receptor proteins, mostly Fe transport. (622 aa)    
Predicted Functional Partners:
pal
OmpA/MotB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
  
 0.941
EED31858.1
Periplasmic protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
   
 
 0.876
EED31677.1
[M] COG1596 Periplasmic protein involved in polysaccharide export.
  
  
  0.867
EED33965.1
[M] COG1596 Periplasmic protein involved in polysaccharide export.
     
  0.848
hmuU
Hemin ABC transporter, permease protein; [P] COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
     0.838
cobO
cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
  
  
 0.836
EED32627.1
Hemin import ATP-binding protein HmuV; [G] COG1129 ABC-type sugar transport system, ATPase component.
 
     0.821
EED31433.1
OmpA/MotB domain protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
     
 0.767
EED31901.1
[M] COG0810 Periplasmic protein TonB, links inner and outer membranes.
   
 
 0.750
EED31060.1
TonB-dependent receptor, plug; [P] COG1629 Outer membrane receptor proteins, mostly Fe transport; overlaps another CDS with the same product name.
  
   
 0.727
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (28%) [HD]